beta-amyloid相关论文
Alzheimer\'s disease is a neurodegenerative condition leading to atrophy of the brain and robbing nearly 5.8 million i......
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Alzheimers disease (AD) is a chronic,progressing neuronal degeneration disease,the etiology and pathogenesis of AD is no......
Modulating balance of synaptic and extrasynaptic NMDA receptors(NMDARs)shows priority over nonselect
OBJECTIVE Alzheimer disease(AD)patients suffer a disturbance in the balance between synaptic NMDARs(NR2A,mediating the p......
Extracellular exosomes are formed inside the cell in compartments known as multivesicular bodies(MVBs)in the cytoplasm,w......
Objective: Beta-amyloid (Aβ) deposition and associated neuroinflammation are considered as important factors leading to......
A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular l......
Icariside Ⅱ, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocininduced cognitive defic
This study was designed to investigate whether icariside Ⅱ (ICS Ⅱ) could ameliorate spatial learning and memory impair......
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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of de-mentia worldwide. A......
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Objective:To observe the effect of the total alkaloids of Dendrobium nobile Lindl on the leing and memory impairment of ......
Curcumin inhibits beta-amyloid protein 40/42 expression in the brain in a concentration-and time-dep
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为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 研究神经调节素1β( neuregulin 1β,NRG1β)对β-淀粉样蛋白1-40(beta-amyloid protein,Aβ1-40)所致的模拟阿尔茨海默病模......
目的 观察二十烷酸对大鼠原代皮质神经元β-淀粉样前体蛋白(APP)及β-分泌酶(BACE1)表达的影响,探讨饱和脂肪酸在阿尔茨海默病发病......
脑源性神经生长因子(brain-derived neurotrophic factor,BDNF)对维持神经元存活、生长、分化及神经损伤后的修复与再生具有十分重......
High levels of the neurotoxic beta-amyloid protein (A<em>β</em>) in patients with Alzheimer’s disease present a signif......
目的探讨雷沙吉兰（Rasagiline）对β-淀粉样蛋白（Ap）诱导PCI2细胞损伤阿尔茨海默病（AD）模型的保护作用及其机制。方法不同浓度的Aβ25-35（1......
目的探讨β-淀粉样蛋白（Aβ1-40）诱导PC12细胞凋亡,对突触素的表达影响。方法星形胶质细胞诱导PC12细胞分化为神经元样细胞。PC12细......
目的 研究Aβ32-35的血管活性机制. 方法 建立鼠后爪垫皮肤微血管网模型,将新鲜制备的Aβ32-35(10μmol)溶液、Ach (100μmol)、SN......
阿尔茨海默病(AD)的病因尚不十分清楚.目前,以β-淀粉样蛋白为中心的生理病理学说被广泛接受.简要描叙该病理过程,从抑制β-淀粉样......
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目的 研究糖尿病小鼠海马内凋亡相关蛋白表达的变化及神经元是否凋亡。同时，观察B淀粉样肽前体蛋白N端17肽(APPl7肽)的作用。方法 ......
Consumption of Oriental Plums Improved the Cognitive Performance and Modulated the Cerebral Neurodeg
To examine the effect of consuming polyphenol-rich Oriental plum (Prunus salicina Lindl) on the cognitive performance an......
As the number of patients with Alzheimer’s disease (AD) continues to rise throughout the twenty- first century, scienti......
目的探讨p38丝裂原活化蛋白激酶（038MAPK）活性在β淀粉样肽（Aβ）＋缺氧缺糖（OGD）所致SHSY5Y细胞损伤中的作用。方法体外培养SHSY5Y神经母细......
Alzheimer’s disease(AD)is a progressive neurodegenerative disorder and the most common form of dementia worldwide.As ag......
目的通过体外实验的方法研究炎性环境促进异常聚集的可溶性β淀粉样蛋白（fibrillar β-amyloid，fAβ）1-42引发神经毒性的分子机制。方......
第一部分：慢性心力衰竭对小鼠行为及beta-Amyloid代谢的影响心力衰竭是一种临床上十分常见的心血管疾病,常常可以继发于心肌梗死、......
Type of the lymphatic system is a new concept put forward by foreign scholars in recent years.It is similar to the lymph......
目的通过体外实验的方法研究炎性环境促进异常聚集的可溶性β-淀粉样蛋白(fibrillarβ-amyloid,fAβ)1-42引发神经毒性的分子机制......
